Characterization, skin permeation of liposomes incorporated hydrophilic or lipophilic compound for transdermal drug delivery system: optimization by computer program
1. To clarify the important fundamental information and the relationships between formulation factor and physicochemical characteristics for simplifying the development of novel liposomal systems for transdermal drug delivery.
2. To optimize the novel liposomal systems as a transdermal drug delivery carrier for enhancing skin permeation of hydrophilic and lipophilic drugs by computer programs, and investigate the novel optimal formulation by the experiment.
3. To formulate the products with the novel liposomal formulation for transdermal drug delivery of both hydrophilic and lipophilic drugs.