1. To investigate the necessities of PC in supporting growth, proliferation and invasion of metastasized breast cancer cell lines.
2 To identify the shuttle that is associated with overexpression of PC in metastasized cancer cell lines.
3. To identify the functional importance of PC in supporting oxidation of ?-oxidation-derived acetyl-CoA in metastasized breast cancer cell lines.
4. To investigate the association between the degree of overexpression of PC and various breast cancer stages in breast tissue samples.
5. To identify the transcription factors which are responsible for transcriptional activation of the PC gene promoter in metastasized breast cancer cell lines.
