In vitro and in vivo investigations of biomarkers indicating clearance stage of Mycobacterium tuberculosis infection after treatment with anti-tuberculous drugs
To investigate the clearance biomarkers for Mtb infection from host cells that can be used to predict the clearance stage of Mtb infection after treatment with anti-tuberculous drugs using human primary cells infection and comparative proteomic analysis and evaluate the potential markers with serum of TB patients treated with anti-tuberculous drugs. The host-pathogen interaction at proteomic level can be additionally investigated.
