การศึกษาความยืนยาวของการตอบสนองทางภูมิคุ้มกันของ Memory B cells และ Neutralizing antibodies จำเพาะต่อสายพันธุ์ polymorphic haplotypes ของวัคซีนแอนติเจน Plasmodium vivax Duffy Binding Protein
Longevity of memory B cells and neutralizing antibody responses against polymorphic haplotypes of Plasmodium vivax Duffy Binding Protein vaccine candidate
1. To observe the kinetic change of B cell subsets during and postinfection with P. vivax.
2. To study longevity of memory B cells and neutralizing antibodies against polymorphic haplotypes of Duffy binding protein in natural P. vivax exposure.
3. To study association of PvDBP-specific memory B cell responses and inhibitory function of neutralizing antibodies against polymorphic Thai DBP haplotypes binding to human erythrocyte
