Effects of titanium surface microtopography and simvastatin on osteoblastic differentiation of human mesenchymal stem cells in osteoporotic model, an in vitro study
a.To investigate effects of titanium surface microtopographies, SLA and mod-SLA surfaces and simvastatin on growth and osteogenic and adipogenic differentiation of estrogen-deficient--hMSCs on titanium surfaces
b.To examine effects of titanium surface topography on expression and functions of Wnt10b on growth and osteogenic differentiation of ED-hMSCs on titanium surfaces.