1 To investigate role of Tregitopes alone or in combination with-/molecularly linked to- major cockroach (CR) allergen (arginine kinase; Per a 9) in inducing regulatory T cell response which suppresses pathogenic Th2 in murine model of CR allergy
2 To identify protein(s) of filarial parasite, Brugia malayi, that can induce Treg response and to use the protein(s) in treatment of allergy in CR allergic mouse model
