The synthesis of cycloalkyl-fused quinolines, indoloquinolines and N-arylisoxazol-5-amines via N2-extrusion of azide: Application for the synthesis of neocryptolepine derivatives for evaluation of anti-cancer activities
1. To develop a novel strategy for the synthesis of cycloalkyl-fused quinolines.
2. To develop a novel strategy for the synthesis of indoloquinolines and study the structure activity relationship of neocryptolepine derivatives for anti-cancer evaluation.
3. To develop a novel strategy for the synthesis of N-arylisoxazol-5-amine.