1. To investigate and elucidate the mechanisms of the illicit substances such as amphetamines affecting early brain development and functions.
2. To investigate and elucidate the mechanisms of amphetamine, trigger cell death and induce age-related neurodegeneration.
3. To investigate certain environmental factors, such as stress affecting early brain development.
4. To investigate and elucidate whether "physical exercise" can enhance the neuronal development, restore of surviving neurons and enhance neurogenesis in aging brain.
5. To identify the roles of neuroprotective agents especially of melatonin and natural phenols like phytoestrogens in developing and adult nerve cells, and the pharmacological potential of the factors to prevent death of the nervous, to maintain their functions and to enhance neurogenesis.
6. To investigate different potential candidate genes involved in drug addiction, in age-related neurodegeneration, in neurona